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J&J Family of Companies Senior Scientist, Proteomics Automation and Workflows - Cambridge, MA in Cambridge, Massachusetts

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Senior Scientist, Proteomics Automation and Workflows, for our site in Cambridge, MA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Redefining lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science.

We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.

This candidate will join our high throughput proteomics, a group within the Discovery Technologies and Molecular Pharmacology (DTMP) department of Discovery Therapeutics, to develop and apply pioneering approaches to proteomic screening and analysis. This effort will support the identification and development of small and large molecule therapeutics for disease indications, including Oncology, Immunology, Infectious Diseases, Neuroscience, and Cardiovascular and Metabolic Diseases. You will work in an exciting, interdisciplinary environment, overlapping the different stages of the discovery pipeline, by interacting with several internal and external groups. You should be highly self-motivated and will be expected to critically analyze and interpret data from a variety of sources. You will provide analytical support for proteomics efforts within the group, for the integration of that screening data with other ‘Omics’ datasets and for the interpretation of that data into clear and concise recommendations for our partners.

Responsibilities:

  • Develop and apply high throughput methodologies for sample preparation, mass spectrometry and data analysis from both in vitro and in vivo experiments, including quality control.

  • Collaborate with colleagues from the various therapeutic areas to craft mass spec based proteomics experiments to answer questions to advance the portfolio

  • Employ automation capabilities to enable the rapid generation of mass spectrometry datasets.

  • Collaborate across multiple subject areas and contribute to various projects within the organization.

  • Demonstrate creativity and apply novel approaches to solving scientific problems. Propose novel and practical ideas, aligned with scientific strategies and demands.

  • Keep up to date on new mass spectrometry based proteomics methodologies and instrumentation, as well as automation for the preparation of proteomics samples.

  • Communicate in a clear and professional manner, both in writing and orally.

Qualifications

  • A minimum of a Bachelor’s or Master’s degree is required (in Analytical Chemistry, Biochemistry, Molecular Biology, Pharmacology, or a related field) or an advanced Ph.D. is preferred.

  • A Bachelor’s degree with a minimum of 5 or more years of proven experience in a biotech/pharmaceutical setting, a Master’s degree with 4 or more years of proven experience in a biotech/pharmaceutical setting -OR- a Ph.D. with 2 or more years or more of post-degree working experience in a biotech/pharmaceutical setting, -OR- Ph.D. with 3 or more years or more of post-degree working experience in an academic research setting is required.

  • Drug discovery experience in a biotech or pharmaceutical environment is preferred.

  • Experience with liquid chromatography (Waters nanoAcquity or Thermo EASY-nLC or UltiMate 3000) and mass spectrometry (Thermo QE, Exploris, Eclipse, Lumos or Bruker timsTOF) instrumentation is required.

  • Proficiency with lab liquid handling automation (Beckman Biomek, Hamilton Microlab STAR, TECAN Fluent) use and programming preferred.

  • Experience with mass spec proteomics quantitative and semi-quantitative sample preparation and analysis required.

  • Experience with collaborating with external partners (e.g. contract research organizations and academics) is preferred.

  • Ability to interpret, troubleshoot and report on complex data is required.

  • Ability to effectively present scientific data and concepts to international standards is required.

  • Strong organizational skills including the ability to handle several projects at a time is required.

  • Excellent interpersonal skills with the ability to interact effectively with diverse colleagues is required.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

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Primary Location

United States-Massachusetts-Cambridge-MA Cambridge Binney

Organization

Janssen Research & Development, LLC (6084)

Job Function

R&D

Requisition ID

2105986830W

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