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J&J Family of Companies Scientist, Antibody Screening in Spring House, Pennsylvania

Scientist, Antibody Screening - 2306148672W


Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Scientist, Antibody Screening located in Spring House, PA.

At Janssen, we never stop working toward a future where disease is a thing of the past. We’re the Pharmaceutical Companies of Johnson & Johnson, and you can count on us to keep working tirelessly to make that future a reality for patients everywhere, by fighting sickness with science, improving access with ingenuity, and healing hopelessness with heart. We focus on areas of medicine where we can make the biggest difference: Cardiovascular & Metabolism, Immunology, Infectious Diseases & Vaccines, Neuroscience, Oncology, and Pulmonary Arterial Hypertension. Visit us: www.janssen.com .

This is a Scientist level position within the High Throughput Screening team in the Biologics Discovery (BD). This group is responsible for discovering and characterizing lead candidates for large molecule biotherapeutic drug development across all therapeutic areas of J&J.

This position supports Biologics Discovery through the collaborative development of cellular and biochemical assays and subsequent screening of therapeutics. The successful candidate will possess knowledge of and experience with large molecule development and screening technologies. The position also requires analysis of the data generated, interpretation of the results, preparation of reports, and effective communication of results to multiple project teams.

Key Responsibilities:

  • Collaborate with Biologics Discovery and Therapeutic Area groups to develop and optimize high throughput assays for screening of antibodies and other large molecules.

  • Design and implement screening cascades for therapeutic programs that result in the accomplishment of team goals for identifying antibodies/proteins meeting the program’s requirements.

  • Act as an individual contributor on therapeutic projects and process improvement.

  • Coordinate with internal groups of scientists responsible for screening activities for binding and functional activity on panels of antibodies generated both internally and externally.

  • Prepare scientific presentations, documents for regulatory filing, and patents.



  • Bachelor degree in Molecular Biology, Biochemistry, Biophysics, Pharmacology, Immunology or a related field with a minimum of 10 years of experience is required or

  • Master degree in Molecular Biology, Biochemistry, Biophysics, Pharmacology, Immunology or a related field with a minimum of 4 years of experience is required or

  • PhD in Molecular Biology, Biochemistry, Biophysics, Pharmacology, Immunology or a related field with a minimum of 1 year of experience is required.

Experience and Skills:


  • Expertise in cell and protein binding assay development against diverse targets, using multiple detection modalities (Flow cytometry, MSD, alphaLISA) is required.

  • Ability to work in a highly coordinated environment, prioritizing multiple projects simultaneously is required.

  • Strong interpersonal and collaboration skills with clear communication skills to build positive relationships with project teams is required.

  • Proficiency in analysis of assay readouts and statistical analysis is required.


  • Knowledge of the therapeutic antibody discovery process in an industry or academic setting is preferred.

  • Experience in developing target-specific functional assays (neutralization/blocking assays, characterization of signalization pathways modulation, agonist/antagonist assays, quantification of enzymatic activity) is preferred.

  • Proficiency in applying automation to screening campaigns is preferred.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com .

Primary Location NA-US-Pennsylvania-Spring House

Organization Janssen Research & Development, LLC (6084)

Job Function R&D

Req ID: 2306148672W